Karzoug was the last Runelord of Greed. He once ruled Fornaven; one of seven Imperial Districts of the lost Iskari Empire.

Karzoug was a specialist in "Greed-Magic" which is now called Transmutation, and was both a powerful wizard and fierce warrior.

For many years, Karzoug ruled from the district capital of Shalast, which was located high in the Hollow Mountains of Ikharos.

During his reign, Karzoug fought several wars against his most hated rival; the Runelord Alaznist.

Karzoug is believed to have been destroyed, along with his six fellow Runelords, during the catastrophic events of Skyfall. Karzoug had a loyal apprentice named Rorskan, whose fate is also unknown.